Dr. Slump is a Japanese manga/anime series by Akira Toriyama.

Dr.Sembei Norimaki decides to create an android with a human appearance to help him with his daily chores. 
The result is little Arale, an android with enormous strength and extraordinary innocence. 
So that no one suspects and finds out that she is not human, Sembei poses as her younger sister. Arale and Sembei will live an endless number of fun and unusual situations...